CNTRL

centriolin

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000119397
UniProt:
Q7Z7A1
OMIM:
605496
Synonyms:
CEP1, CEP110

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Elliott et al. 2025 (CRISPRa) [CRISPRa]: Disassembly Trigger (casTLE Effect=-2.77) PMID:41160700

Subcellular localization

basal body

References: PMID:41005307, PMID:27340223

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation
  • Protein processing & maturation
  • Signaling (Hedgehog, GPCRs, ion channels)
  • Cardiac & muscle development

Function

CNTRL has localized in basal body.