COX6B1

cytochrome c oxidase subunit 6B1

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000126267
UniProt:: P14854
OMIM:: 124089
Synonyms:: COX6B, COXG

Ciliogenesis screen results (4 screens)

Kim2016: Not Reported
Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:: abnormal skin morphology, abnormal embryo size, preweaning lethality, complete penetrance, abnormal sinus arrhythmia, increased spleen weight

Subcellular localization

flagella, mitochondria

References: PMID:25613900

Function

COX6B1 has localized in flagella.

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