COX6B1

cytochrome c oxidase subunit 6B1

Ensembl:
ENSG00000126267
UniProt:
P14854
OMIM:
124089
Synonyms:
COX6B, COXG

Cilia effects upon perturbation of COX6B1

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
abnormal skin morphology, abnormal embryo size, preweaning lethality, complete penetrance, abnormal sinus arrhythmia, increased spleen weight
Mouse ciliopathy phenotype:
microphthalmia, absent adrel gland

Subcellular localization

flagella, mitochondria

Function

COX6B1 has localized in flagella.