CRTAP

cartilage associated protein

Ensembl:
ENSG00000170275
UniProt:
O75718
OMIM:
605497
Synonyms:
CASP, LEPREL3, P3H5

Cilia effects upon perturbation of CRTAP

Ciliogenesis screen results (5 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
  • Pusapati et al. 2018 (CRISPR) [CRISPR]: Negative Regulator (Hh signaling, pos_rank=223, lfc=0.53) PMID:30270045

Subcellular localization

actin filaments, cytosol, intermediate filaments

Function

Mutations in CRTAP cause Carpenter Syndrome (PMID: 25604815; 29384951).