CSNK1G1

casein kinase 1 gamma 1

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000169118
UniProt:: Q9HCP0
OMIM:: 606274
Synonyms:: CK1GAMMA1

Ciliogenesis screen results (4 screens)

Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-3.42) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
Elliott et al. 2025 (CRISPRa) [CRISPRa]: Disassembly Trigger (casTLE Effect=-3.40) PMID:41160700

Phenotypes

Mouse phenotype:: increased leukocyte cell number, increased mean corpuscular hemoglobin, increased grip strength, hyperactivity, increased exploration in new environment, increased mean corpuscular volume

Subcellular localization

cilia

References: PMID:40623838

Functional category

Ciliary assembly/disassembly

Function

CSNK1G1 and CSNK1G3 highly specificly localized to neuronal primary cilia (PMID: 40623838).

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