CSNK1G3

casein kinase 1 gamma 3

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000151292
UniProt:: Q9Y6M4
OMIM:: 604253

Ciliogenesis screen results (4 screens)

Kim2016: Not Reported
Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.58) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:: increased mean corpuscular hemoglobin, absent pin reflex, decreased circulating fructosamine level, decreased hematocrit, decreased bone mineral content, decreased body length, decreased erythrocyte cell number, decreased circulating alkaline phosphatase level, increased circulating ldl cholesterol level

Subcellular localization

cilia

References: PMID:40623838

Functional category

Ciliary assembly/disassembly

Function

CSNK1G1 and CSNK1G3 highly specificly localized to neuronal primary cilia (PMID: 40623838).

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