CTSB

cathepsin B

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000285132
UniProt:
P07858
OMIM:
116810

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-3.29) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia, lysosomes, nucleoli, vesicles

References: PMID:41410385, PMID:41005307

Functional category

  • Trafficking (BBSome, small GTPases, vesicular transport, ATPases)

Function

CTSB has located to motile cilia.