DCTN3
dynactin subunit 3
- Ensembl:
- ENSG00000137100
- UniProt:
- O75935
- OMIM:
- 607387
- Synonyms:
- DCTN-22
Cilia effects upon perturbation of DCTN3
Ciliogenesis screen results (2 screens)
- Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.52) PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Subcellular localization
centrosome, cytosol, flagella
Functional category
- Ciliary assembly/disassembly
- Actin & cytoskeleton regulation
- Protein processing & maturation
- Signaling (Hedgehog, GPCRs, ion channels)
Function
DCTN3 has localized in flagella.