DDX25

DEAD-box helicase 25

Ensembl:
ENSG00000109832
UniProt:
Q9UHL0
OMIM:
607663
Synonyms:
GRTH

Cilia effects upon perturbation of DDX25

Ciliogenesis screen results (5 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-5.80) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
  • Pusapati et al. 2018 (CRISPR) [CRISPR]: Negative Regulator (Hh signaling, pos_rank=299, lfc=0.23) PMID:30270045

Subcellular localization

cytosol, nucleoplasm

Function

Mutations in DDX25 cause Hydrolethalus Syndrome (PMID: 15843405).