DMBT1

deleted in malignant brain tumors 1

Ensembl:
ENSG00000187908
UniProt:
Q9UGM3
OMIM:
601969
Synonyms:
GP-340, GP340, SALSA

Cilia effects upon perturbation of DMBT1

Ciliogenesis screen results (5 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
  • Kim et al. 2010 (siRNA) [siRNA]: Shorter Cilia (Area per Cilia z=-2.15) PMID:20393562

Subcellular localization

basal body

Functional category

  • Ciliary assembly/disassembly
  • Cell migration & adhesion
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

Treatment with human recombi nt DMBT1 decreases ciliary motility of human ciliated respiratory epithelial cells in vitro (35249163). DMBT1 localized to basal body (25613900)