DNAH10

dynein axonemal heavy chain 10

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000281935
UniProt:: Q8IVF4
OMIM:: 605884
Synonyms:: FLJ43808

Ciliogenesis screen results (3 screens)

Kim2016: Not Reported
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia

References: PMID:41410385, PMID:42010243, PMID:11175280, PMID:15937072, PMID:25927852

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation
Metabolism
Cell migration & adhesion

Function

Component of outer dynein arm (PMID:15937072, 11175280, 29843777). Heterotaxy candidate gene, involved in left-right patterning regulaton by affecting the notochord. Participates in protozoan flagellar motility (29843777)

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