DNAH7

dynein axonemal heavy chain 7

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000118997
UniProt:
Q8WXX0
OMIM:
610061
Synonyms:
KIAA0944

Ciliogenesis screen results (2 screens)

  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Ciliopathy associations

  • Primary Ciliary Dyskinesia

References: PMID:11877439

Subcellular localization

cilia, flagella

References: PMID:41410385, PMID:11877439

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation
  • Metabolism
  • Cell migration & adhesion

Function

Axonemal inner arm component of human cilia. Absent in primary ciliary dyskinesia (11877439)