DNAI7

dynein axonemal intermediate chain 7

Ensembl:: ENSG00000118307
UniProt:: Q6TDU7
OMIM:: 616906
Synonyms:: CASC1, CFAP94, FLJ10921, LAS1, PPP1R54

Cilia effects upon perturbation of DNAI7

Subcellular localization

cilia, cytosol, vesicles

Functional category

Motors (dynein/kinesin)
Trafficking (BBSome, small GTPases, vesicular transport, ATPases)

Function

DNAI7 has located to motile cilia.

Model organism evidence

Mus musculus (1 reference)

This study aimed to elucidate the pathogenic mechanism linking CFAP251 deficiency to human male infertility and to determine whether CFAP251 plays an active role in both flagella and cilia across species.

PMIDs: 41943837

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