DNAL4
dynein axonemal light chain 4
- Ensembl:
- ENSG00000100246
- UniProt:
- O96015
- OMIM:
- 610565
- Synonyms:
- DJ327J16, PIG27
Cilia effects upon perturbation of DNAL4
Ciliogenesis screen results (3 screens)
- Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-5.06) PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
- Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
Phenotypes
- Mouse phenotype:
- tremors, preweaning lethality, incomplete penetrance, decreased exploration in new environment
Subcellular localization
basal body
Functional category
- Ciliary assembly/disassembly
- Actin & cytoskeleton regulation
Function
D L4 localized basal body