DRC9

IQ motif containing G

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000114473
UniProt:: Q9H095
OMIM:: 612477
Synonyms:: CFAP122, DKFZP434B227, IQCG

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

basal body, cilia

References: PMID:42010243, PMID:25139857, PMID:24849454

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation
Reproduction & sperm
Protein processing & maturation
Cell migration & adhesion

Function

Required for cilogenesis and spermiogenesis in mammals through a dynamic interaction with calmodulin in different intracellular calcium levels (24849454).

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