EFNB1

ephrin B1

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000090776
UniProt:
P98172
OMIM:
300035
Synonyms:
CFNS, ELK-L, EPLG2, LERK2

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia, nucleus

References: PMID:40623838

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation
  • Neurogenesis & migration
  • Cell migration & adhesion
  • Signaling (Hedgehog, GPCRs, ion channels)
  • Axon guidance & growth

Function

EFNB1, EFNB2, and EPHA4 proteins colocalize or partially colocalize with Arl13b (PMID: 40623838).