ENO2

enolase 2

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000111674
OMIM:: 131360
Synonyms:: NSE

Phenotypes

Mouse phenotype:: prolonged QRS complex duration

Subcellular localization

cilia, Plasma membrane, Cytosol

References: PMID:34083607

Function

The genome of Tetrahymena encodes three enolases, Eno1 (TTHERM_00486480), Eno2 (TTHERM_00046480), and Eno3 (TTHERM_ 00,474,960). Eno1 and Eno2 were detected in wild-type cilia. In the CFAP69-KO and SPEF2A-coDel cilia, the levels of Eno1 were reduced, but surprisingly, the level of Eno2 was higher in SPEF2A-coDel than in the wild-type cilia (Tables 3, S6)(34083607).

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