EPB41L2

erythrocyte membrane protein band 4.1 like 2

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000079819
UniProt:
O43491
OMIM:
603237
Synonyms:
4.1-G, 4.1G

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia

References: PMID:36776558, doi:10.1101/2025.05.11.653368

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation

Function

EPB41L2, erythrocyte membrane protein band 4.1 like 2, localised to cilia(36776558) . Detected in primary cilia of human hypothalamic neurons by proximity proteomics (Macarelli et al., 2025, bioRxiv, doi 10.1101/2025.05.11.653368).