EPRS1

glutamyl-prolyl-tRNA synthetase 1

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000136628
UniProt:: P07814
OMIM:: 138295
Synonyms:: EARS, EPRS, GLUPRORS, PARS, QARS, QPRS

Phenotypes

Mouse phenotype:: preweaning lethality, complete penetrance, abnormal lung morphology, decreased prepulse inhibition, abnormal embryo size, embryonic lethality prior to tooth bud stage, embryonic lethality prior to organogenesis

Subcellular localization

flagella

References: PMID:25613900

Functional category

Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
Transcription regulation

Function

EPRS1 has localized in flagella.

Note: Additional interactive sections (perturbation matrix visualization, phylogenetic conservation strip, protein complex network, STRING interactions) require JavaScript. Browse CiliaHub for the full experience.