FAM186B

family with sequence similarity 186 member B

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000135436
UniProt:: Q8IYM0
Synonyms:: C12ORF25, DKFZP434J0113

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Mouse phenotype:: increased circulating hdl cholesterol level, increased fasting circulating glucose level, increased circulating sodium level

Subcellular localization

cilia, basal body

References: PMID:41005307

Functional category

Ciliary assembly/disassembly

Function

FAM186B has localized in cilia.

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