FBXL13

F-box and leucine rich repeat protein 13

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000161040
UniProt:
Q8NEE6
OMIM:
609080
Synonyms:
CFAP169, DRC6, FBL13, MGC21636

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

flagella

References: PMID:31961863

Function

Mutated Fbxl13 and Drc7, two genes with strong expression in mouse testis and which have been shown to be important for flagellum formation and regulation in other systems (31961863).