FDXR

ferredoxin reductase

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000161513
UniProt:
P22570
OMIM:
103270
Synonyms:
AR, ADXR, ADR

Ciliogenesis screen results (4 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-5.46) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: Increased Signaling (Negative Regulator) PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
  • Elliott et al. 2025 (CRISPRa) [CRISPRa]: Disassembly Trigger (casTLE Effect=-3.27) PMID:41160700

Subcellular localization

cilia, mitochondria

References: PMID:41410385

Function

FDXR has located to motile cilia.