FOXA2

forkhead box A2

Tier: Cilia-Associated Genes

Ensembl:: ENSG00000125798
UniProt:: Q9Y261
OMIM:: 600288
Synonyms:: HNF3B

Ciliogenesis screen results (4 screens)

Kim2016: Not Reported
Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-4.85) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

nucleus

References: PMID:16239640

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation
Cell migration & adhesion
Transcription regulation

Function

Foxa1, Foxa2, and Foxj1 were dynamically regulated after injury and restoration of the bronchiolar epithelium, the highest levels of expression being observed in ciliated cells and their derivatives early in the repair process ( 16239640).

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