FPR3
formyl peptide receptor 3
- Ensembl:
- ENSG00000187474
- UniProt:
- P25089
- Synonyms:
- FMLPY, FPRH1, FPRL2, RMLP-R-I
Cilia effects upon perturbation of FPR3
Ciliogenesis screen results (1 screen)
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Phenotypes
- Mouse phenotype:
- abnormal colon morphology, increased hematocrit, abnormal ileum morphology, decreased exploration in new environment, increased hemoglobin content, increased circulating cholesterol level
- Mouse ciliopathy phenotype:
- persistence of hyaloid vascular system, abnormal vitreous body morphology
Subcellular localization
cilia
Functional category
- Ciliary assembly/disassembly
- Signaling (Hedgehog, GPCRs, ion channels)
Function
FPR3 has localized in cilia.