FSCB

fibrous sheath CABYR binding protein

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000189139
UniProt:: Q5H9T9
OMIM:: 611779
Synonyms:: C14ORF155, DKFZP434F1017

Ciliogenesis screen results (1 screens)

Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Mouse phenotype:: hyperactivity, decreased total reti thickness, abnormal reti inner nuclear layer morphology, increased vertical activity, abnormal reti outer nuclear layer morphology

Subcellular localization

flagella

References: PMID:17855365

Functional category

Reproduction & sperm

Function

FSCB serum recognized with an intense signal the entire length of the principal piece of both non-fixed, air dried and methanol-fixed non-capacitated sperm by indirect immunofluorescence microscopy (17855365).

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