FZD5

frizzled class receptor 5

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000163251
OMIM:
601723
Synonyms:
C2ORF31, DKFZP434E2135, HFZ5

Subcellular localization

cilia

References: PMID:36693320

Functional category

  • Signaling (Hedgehog
  • GPCRs
  • ion channels)

Function

We confirmed39 GSK3β localization in primary cilia (Figure 4C) with an antibody validated by siGSK3β RNA knockdown (Figure S4E). The reported presence in cilia of the WNT receptor Frizzled 5 (FZD5)41 was confirmed using overexpression (Figure 4D)(36693320).