GABRA1

gamma-aminobutyric acid type A receptor subunit alpha1

Ensembl:
ENSG00000022355
UniProt:
P14867
OMIM:
137160
Synonyms:
EJM5

Cilia effects upon perturbation of GABRA1

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Ciliopathy associations

  • Juvenile Myoclonic Epilepsy

Subcellular localization

cilia associated gene

Functional category

  • Ciliary assembly/disassembly
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

Neuronal cilia dataset contained eight subspecific GABA receptors that include the GABAA receptors, GABRG2 and GABRA1, and the GABAB receptor, GABBR1(PMID: 40623838).