GABRA1

gamma-aminobutyric acid type A receptor subunit alpha1

Tier: Cilia-Associated Genes

Ensembl:: ENSG00000022355
UniProt:: P14867
OMIM:: 137160
Synonyms:: EJM5

Ciliogenesis screen results (3 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Ciliopathy associations

Juvenile Myoclonic Epilepsy

References: PMID:11992121

Subcellular localization

No ciliary localization reported (cilia-associated gene).

References: PMID:41005307, PMID:36350286, PMID:40623838

Functional category

Ciliary assembly/disassembly
Signaling (Hedgehog, GPCRs, ion channels)

Function

Neuronal cilia dataset contained eight subspecific GABA receptors that include the GABAA receptors, GABRG2 and GABRA1, and the GABAB receptor, GABBR1(PMID: 40623838).

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