GCK

glucokinase

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000106633
UniProt:: P35557
OMIM:: 138079
Synonyms:: HK4, MODY2, GK, GLK

Subcellular localization

cilia

References: PMID:42182460

Functional category

Metabolism

Function

Glucokinase (GCK), the rate-limiting enzyme of upper glycolysis, localizes to primary cilia of human and mouse pancreatic islet beta cells, which contain the complete glycolytic machinery for local ATP production (PMID 42182460).

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