GFRAL

GDNF family receptor alpha like

Ensembl:
ENSG00000187871
UniProt:
Q6UXV0
OMIM:
617837
Synonyms:
BA360D14.1, C6ORF144, GRAL, UNQ9356

Cilia effects upon perturbation of GFRAL

Ciliogenesis screen results (2 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

cilia

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

GFRAL in primary cilia and altered cilia morphology upon GDF15 ablation (38719753).