GLG1

golgi glycoprotein 1

Ensembl:
ENSG00000090863
UniProt:
Q92896
OMIM:
600753
Synonyms:
CFR-1, ESL-1, MG-160

Cilia effects upon perturbation of GLG1

Ciliogenesis screen results (5 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
  • Kim et al. 2010 (siRNA) [siRNA]: Longer Cilia (Area per Cilia z=5.13) PMID:20393562

Phenotypes

Mouse phenotype:
preweaning lethality, incomplete penetrance, abnormal vertebral arch morphology, increased circulating triglyceride level, increased circulating glycerol level

Subcellular localization

flagella

Functional category

  • Protein processing & maturation
  • Signaling (Hedgehog, GPCRs, ion channels)
  • ECM & connective tissue

Function

GLG1 has localized in flagella.