GNAI3

G protein subunit alpha i3

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000065135
UniProt:
P08754
OMIM:
139370
Synonyms:
87U6

Ciliogenesis screen results (4 screens)

  • Kim2016: No effect
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-3.44) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

basal body, centrosome

References: PMID:41005307

Functional category

  • Ciliary assembly/disassembly
  • Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
  • Viral interactions
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

GNAI3 has localized in basal body.