GNAT3

G protein subunit alpha transducin 3

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000214415
UniProt:
A8MTJ3
OMIM:
139395
Synonyms:
GDCA, GUSTDUCIN

Ciliogenesis screen results (2 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-4.19) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

cilia, basal body

References: PMID:41005307, PMID:19628819

Functional category

  • Ciliary assembly/disassembly
  • Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
  • Metabolism
  • Viral interactions
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

α-gustducin and TRPM5 resided in cilia(19628819).