GSTM2

glutathione S-transferase mu 2

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000213366
UniProt:
P28161
OMIM:
138380
Synonyms:
GST4

Ciliogenesis screen results (4 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
  • Failler/Valderrama et al. 2021 (siRNA) [siRNA]: Negative Regulator (Ciliogenesis Candidate) PMID:33206585

Subcellular localization

cilia, cytosol, ciliary tip, transition zone

References: PMID:41005307

Functional category

  • Ciliary assembly/disassembly
  • Signaling (Hedgehog, GPCRs, ion channels)
  • Cardiac & muscle development
  • Muscle contraction & physiology

Function

GSTM2 has localized in ciliary tip, primary cilia.