GSTM4
glutathione S-transferase mu 4
- Ensembl:
- ENSG00000168765
- UniProt:
- Q03013
- OMIM:
- 138333
Cilia effects upon perturbation of GSTM4
Ciliogenesis screen results (2 screens)
- Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-3.48) PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Phenotypes
- Mouse phenotype:
- abnormal spleen morphology, abnormal skin coloration
Subcellular localization
cilia, cytosol, transition zone
Functional category
- Ciliary assembly/disassembly
- Actin & cytoskeleton regulation
- Transition zone
Function
GSTM4 has localized in ciliary tip, transition zone. Mainly localized to the cytosol. In addition localized to the microtubules, cytokinetic bridge, primary cilium, primary cilium tip and primary cilium transition zone.