GSTM4

glutathione S-transferase mu 4

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000168765
UniProt:: Q03013
OMIM:: 138333

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-3.48) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Mouse phenotype:: abnormal spleen morphology, abnormal skin coloration

Subcellular localization

cilia, cytosol, transition zone, ciliary tip

References: PMID:41005307

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation
Transition zone

Function

GSTM4 has localized in ciliary tip, transition zone. Mainly localized to the cytosol. In addition localized to the microtubules, cytokinetic bridge, primary cilium, primary cilium tip and primary cilium transition zone.

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