H3-3B

H3.3 histone B

Ensembl:: ENSG00000132475
UniProt:: P84243
OMIM:: 601058
Synonyms:: H3.3B, H3F3B

Cilia effects upon perturbation of H3-3B

Phenotypes

Mouse phenotype:: increased circulating cholesterol level, increased startle reflex
Mouse ciliopathy phenotype:: abnormal kidney morphology, polycystic kidney

Subcellular localization

flagella

Functional category

Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
Reproduction & sperm
Protein processing & maturation
Signaling (Hedgehog, GPCRs, ion channels)
Cardiac & muscle development
Transcription regulation

Function

H3-3B has localized in flagella.

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