HAUS1

HAUS augmin like complex subunit 1

Ensembl:
ENSG00000152240
UniProt:
Q96CS2
OMIM:
608775
Synonyms:
CCDC5, FLJ40084, HEI-C, HST1461

Cilia effects upon perturbation of HAUS1

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: Increased Signaling (Negative Regulator) PMID:29459680
  • Pusapati et al. 2018 (CRISPR) [CRISPR]: Negative Regulator (Hh signaling, pos_rank=328, lfc=0.32) PMID:30270045

Subcellular localization

centrosome, flagella

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation
  • Protein processing & maturation

Function

HAUS1 has localized in flagella.