HK1

hexokinase 1

Tier: Cilia-Associated Genes

Ensembl:
ENSG00000156515
UniProt:
P19367
OMIM:
142600

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-3.48) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Human ciliopathy phenotype:
retinitis pigmentosa

Subcellular localization

cytosol

Functional category

  • Ciliary assembly/disassembly
  • Metabolism

Function

Mutations in the HK1 gene cause Retinitis Pigmentosa (PMID: 25316723).