HSPA1L

heat shock protein family A (Hsp70) member 1 like

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000234258
UniProt:
P34931
OMIM:
140559
Synonyms:
HSP70-HOM, HUM70T

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.01) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

basal body, cytosol, flagella

References: PMID:25613900

Functional category

  • Ciliary assembly/disassembly
  • Metabolism
  • Viral interactions
  • Protein processing & maturation
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

HSPA1L has localized in basal body,flagella.