IMMP2L

inner mitochondrial membrane peptidase subunit 2

Ensembl:
ENSG00000184903
UniProt:
Q96T52
OMIM:
605977
Synonyms:
IMMP2L-IT1, IMP2

Cilia effects upon perturbation of IMMP2L

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-5.39) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
decreased prepulse inhibition, decreased lean body mass, decreased body length

Subcellular localization

basal body, flagella, mitochondria

Functional category

  • Ciliary assembly/disassembly
  • Reproduction & sperm
  • Protein processing & maturation

Function

IMMP2L has localized in basal body,flagella.