ITLN1

intelectin 1

Ensembl:
ENSG00000179914
UniProt:
Q8WWA0
OMIM:
609873
Synonyms:
FLJ20022, HINTL, HL-1, ITLN, LFR

Cilia effects upon perturbation of ITLN1

Ciliogenesis screen results (5 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-4.36) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
  • Pusapati et al. 2018 (CRISPR) [CRISPR]: Negative Regulator (Hh signaling, pos_rank=95, lfc=0.83) PMID:30270045
  • Elliott et al. 2025 (CRISPRa) [CRISPRa]: Disassembly Trigger (casTLE Effect=-6.60) PMID:41160700

Subcellular localization

flagella

Functional category

  • Actin & cytoskeleton regulation

Function

ITLN1 has localized in flagella.