KCNC1

potassium voltage-gated channel subfamily C member 1

Ensembl:: ENSG00000129159
UniProt:: P48547
OMIM:: 176258
Synonyms:: KV3.1

Cilia effects upon perturbation of KCNC1

Ciliogenesis screen results (4 screens)

Kim2016: Not Reported
Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.19) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

basal body

Functional category

Ciliary assembly/disassembly
Signaling (Hedgehog, GPCRs, ion channels)

Function

KCNC family members (KCNC1, KCNC2, KCNC3, KCNC4) may be involved in ciliated neuro l compartments, based on strong homology and functio l parallels with C. elegans EGL-36, which localizes to the periciliary region of ciliated sensory neurons (33688626).

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