KCNC2

potassium voltage-gated channel subfamily C member 2

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000166006
UniProt:: Q96PR1
OMIM:: 176256
Synonyms:: KV3.2

Ciliogenesis screen results (3 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

basal body

References: PMID:33688626

Functional category

Ciliary assembly/disassembly
Metabolism
Signaling (Hedgehog, GPCRs, ion channels)

Function

KCNC family members (KCNC1, KCNC2, KCNC3, KCNC4) may be involved in ciliated neuronal compartments, based on strong homology and functional parallels with C. elegans EGL-36, which localizes to the periciliary region of ciliated sensory neurons (33688626).

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