KCNC2

potassium voltage-gated channel subfamily C member 2

Ensembl:: ENSG00000166006
UniProt:: Q96PR1
OMIM:: 176256
Synonyms:: KV3.2

Cilia effects upon perturbation of KCNC2

Ciliogenesis screen results (3 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

basal body

Functional category

Ciliary assembly/disassembly
Metabolism
Signaling (Hedgehog, GPCRs, ion channels)

Function

KCNC family members (KCNC1, KCNC2, KCNC3, KCNC4) may be involved in ciliated neuro l compartments, based on strong homology and functio l parallels with C. elegans EGL-36, which localizes to the periciliary region of ciliated sensory neurons (33688626).

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