KIF20B

kinesin family member 20B

Ensembl:: ENSG00000138182
UniProt:: Q96Q89
OMIM:: 605498
Synonyms:: CT90, KRMP1, MPHOSPH1, MPP1

Cilia effects upon perturbation of KIF20B

Cilia number / % ciliated:: Unknown
Loss-of-function effect:: Unknown
Overexpression effect:: Unknown

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

basal body, centrosome, nucleus

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation
Metabolism

Function

KIF20B has localized in basal body.

Model organism evidence

Mus musculus (1 reference)

CASK interacts with PMCA4b and JAM-A on the mouse sperm flagellum to regulate Ca2+ homeostasis and motility.

PMIDs: 22020416

Danio rerio (1 reference)

MPP1 and whirlin colocalize in the retina at the OLM, at the outer synaptic layer and at the basal bodies and the ciliary axoneme.

PMIDs: 17584769

Drosophila (1 reference)

MPP1 and whirlin colocalize in the retina at the OLM, at the outer synaptic layer and at the basal bodies and the ciliary axoneme.

PMIDs: 17584769

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