KIF26B
kinesin family member 26B
- Ensembl:
- ENSG00000281216, ENSG00000162849
- UniProt:
- Q2KJY2
- OMIM:
- 614026
- Synonyms:
- FLJ10157
Cilia effects upon perturbation of KIF26B
- Cilia number / % ciliated:
- Unknown
- Loss-of-function effect:
- Unknown
- Overexpression effect:
- Unknown
Ciliogenesis screen results (4 screens)
- Kim2016: Not Reported
- Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-4.65) PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
- Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
Phenotypes
- Mouse phenotype:
- hyperactivity, decreased circulating free fatty acids level, preweaning lethality, complete penetrance
- Mouse ciliopathy phenotype:
- increased heart weight
Subcellular localization
cilia
Functional category
- Ciliary assembly/disassembly
- Actin & cytoskeleton regulation
- Cell migration & adhesion
Function
KIF26B localized at cilia