KIF26B

kinesin family member 26B

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000281216
UniProt:: Q2KJY2
OMIM:: 614026
Synonyms:: FLJ10157

Cilia effects upon perturbation of KIF26B

Cilia number / % ciliated:: Unknown
Loss-of-function effect:: Unknown
Overexpression effect:: Unknown

Ciliogenesis screen results (4 screens)

Kim2016: Not Reported
Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-4.65) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:: hyperactivity, decreased circulating free fatty acids level, preweaning lethality, complete penetrance

Subcellular localization

cilia

References: PMID:41005307

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation
Cell migration & adhesion

Function

KIF26B localized at cilia

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