KYNU

kynureninase

Ensembl:
ENSG00000115919
UniProt:
Q16719
OMIM:
605197

Cilia effects upon perturbation of KYNU

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-3.04) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Human ciliopathy phenotype:
vertebral, cardiac, renal, and limb defects syndrome 2; congenital vertebral-cardiac-renal anomalies syndrome

Subcellular localization

cilia, cytosol, nucleoplasm

Function

KYNU has located to motile cilia.