LDLRAD1

low density lipoprotein receptor class A domain containing 1

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000203985
UniProt:: Q5T700

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-6.32) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Mouse phenotype:: decreased circulating alkaline phosphatase level, decreased circulating total protein level, abnormal skin coloration, decreased circulating serum albumin level

Subcellular localization

cilia

References: PMID:41410385, PMID:42010243, PMID:41005307

Functional category

Ciliary assembly/disassembly
Signaling (Hedgehog, GPCRs, ion channels)

Function

LDLRAD1 has localized in cilia.

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