LRRC74A

leucine rich repeat containing 74A

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000100565
Synonyms:: C14ORF166B, LRRC74

Subcellular localization

motile cilia

Function

LRRC74A — A motile cilia protein, associated with the N-DRC or related axonemal regulatory structures(39743588). Identified by cryo-EM as a component of the nexin-dynein regulatory complex in sperm flagella and other motile cilia (Leung et al., 2025, Nature, PMID 39743588).

Note: Additional interactive sections (perturbation matrix visualization, phylogenetic conservation strip, protein complex network, STRING interactions) require JavaScript. Browse CiliaHub for the full experience.