MAP4K5

mitogen-activated protein kinase kinase kinase kinase 5

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000012983
UniProt:
Q9Y4K4
OMIM:
604923
Synonyms:
GCKR, KHS, KHS1

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.75) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia

References: PMID:41005307

Functional category

  • Ciliary assembly/disassembly

Function

MAP4K5 has localized in primary cilia.