MC3R

melanocortin 3 receptor

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000124089
OMIM:: 155540
Synonyms:: MC3

Phenotypes

Mouse phenotype:: small kidney, small testis, abnormal kidney morphology, abnormal testis morphology

Subcellular localization

cilia

References: PMID:36692018

Functional category

Small GTPases
Non-motile cilium / primary cilium
Signaling (Hedgehog
GPCRs
ion channels)

Function

MC3R localizes to the primary cilium in IMCD3 cells, with MRAP2 strongly enhancing its ciliary localization(36512344).

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