?

Phenotypes

Mouse phenotype:

small kidney, small testis, abnormal kidney morphology, abnormal testis morphology

Subcellular localization

cilia

Functional category

• Small GTPases
• Non-motile cilium / primary cilium
• Signaling (Hedgehog
• GPCRs
• ion channels)

Function

MC3R localizes to the primary cilium in IMCD3 cells, with MRAP2 strongly enhancing its ciliary localization(36512344).