MC5R

melanocortin 5 receptor

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000176136
OMIM:: 600042

Phenotypes

Mouse phenotype:: abnormal brain morphology, abnormal testis morphology, enlarged testis, cataract, abnormal vitreous body morphology

Subcellular localization

cilia, Plasma membrane

References: PMID:36692018

Functional category

Small GTPases
Non-motile cilium / primary cilium
Signaling (Hedgehog
GPCRs
ion channels)

Function

MC5R localizes to the primary cilium in IMCD3 cells, and MRAP2 promotes its enrichment within the ciliary compartment(36512344).

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