MCHR2
melanin concentrating hormone receptor 2
- Ensembl:
- ENSG00000152034
- UniProt:
- Q969V1
- OMIM:
- 606111
- Synonyms:
- GPR145, MCH2, MCH2R, SLT
Cilia effects upon perturbation of MCHR2
Subcellular localization
basal body, cilia
Functional category
- Ciliary assembly/disassembly
- Signaling (Hedgehog, GPCRs, ion channels)
Function
MCHR2 has localized in basal body, cilia.
Model organism evidence
Mus musculus (2 references)
Our results show that MCHR1 is abundantly found in a subcellular structure called the primary cilium, which has been associated, among other functions, with the detection of free neurochemical messengers present in the extracellular space.
Recently, MCHR1 expression was discovered in neuronal immotile primary cilia of the central nervous system in mice.